The Murray hardyhead (Craterocephalus fluviatilis) is a small and short-lived (1–2year) native freshwater fish, with a tolerance for highly saline waters. As a result of habitat loss, river regulation and pest species, Murray hardyhead have diminished in abundance and distribution and are currently absent across much of their former range. In November 2018, approximately 800 individuals were successfully translocated from managed South Australian wetlands into a salt affected wetland in southwest NSW. Salinity in the translocation wetland was regulated via the delivery of environmental water to manage predators, pest fish, and stimulate productivity and breeding. Subsequent monitoring indicates regular annual breeding and recruitment success following translocation. This translocation represents the first attempt in NSW to re-establish a regionally extinct native fish, and is founded on strong collaboration between NSW, South Australian and federal agencies, environmental water managers and the owner/managers of the relocation wetland.